X-omics @ Radboud Summer School

This year X-omics will organise an online course again in the Radboud Summer School: Integrative X-omics Analyses Empowering Personalised Healthcare. This course will take place from 5-9 July 2021.

Course leaders:

P.A.C. ’t Hoen, Professor of Bioinformatics
Center for Molecular and Biomolecular Informatics 
Radboud University Medical Center

A.J. van Gool, Professor Personalized Healthcare 
Laboratory Medicine 
Radboud University Medical Center

More information about this course and the summer school can be found at:

X-omics helpdesk - pitch your project and get expert advice

Are you seeking expert advice on experimental design and data integration strategies for a multi-omics approach on your own research project? Register for a pitch your project helpdesk meeting, public or privately!

We received a lot of registrations for the pitch your project sessions in both X-omics workshop series and decided to have these meetings more frequently.

Provide us with your project information via the pitch your project registration and one of the organizers will reach out to you to schedule a meeting. You can choose for a public or private meeting.

Pitch your project

Update X-omics festival 2021

On  April 12th 2021, the third edition of the X-omics festival will take place ONLINE!

It is too uncertain what the coronavirus measurements in April 2021 will be. By making this decision now, we can fully direct our attention to preparing an entertaining and interactive 3rd online edition of the X-omics festival.

We hope to see you all during the festival!

Online multi-omics data integration workshop series

We are inviting you to an online workshop series on multi-omics data integration, starting in January, 2021.

Workshop #1: "Multi-omics helpdesk, data-centric analysis platform and NGS diagnostics case study".
Wednesday, January 20, 2021, 15:00 – 17:00 CET.

Workshop #2: "Multi-omics integration tools and platforms".
Wednesday, February 10, 2021, 15:00 – 17:00 CET.

Workshop #3: "Predictive multi-omics biomarker signatures".
Wednesday, February 24, 2021, 15:00 – 17:00 CET.

Workshop #4: “Pitch your own research project”.
Wednesday, March 10, 2021, 15:00 – 17:00 CET.

This workshop series is a collaboration of X-omics, BBMRI-NL, Health-RI and Eatris(-Plus).

More information 

Make sure to register yourself!

Registration online workshop series

Seeding grant for Neurolipid Atlas project

X-omics member Martin Giera (LUMC) and Rik van der Kant (VUMC) received a Chan Zuckerberg Initiative (CZI) seeding grant of $150,000 for their Neurolipid Atlas project. With this project, they are the first Dutch researchers to join the Neurodegeneration Challenge Network (NDCN), founded by CZI.

This project aims to analyze the lipidome of human iPSC-derived neurons and glia, gene-edited for specific disease variants, and will generate the first map of disease-specific, genotype-specific and cell type-specific changes in the human lipidome associated with neurodegenerative diseases.

More information about this project

If their project will have a successful evaluation after 18 months, they may qualify for a supplementary grant of $1.6 million for the next 4 years.

X-omics YouTube channel

Do you know that X-omics has its own YouTube channel?

All kinds of videos and recordings are already shared here:

In the coming years, more of these type of videos will be uploaded.

The aftermovie of the X-omics festival 2020 will be online soon! Go subscribe to our channel, so you will know when it is online.

X-omics YouTube channel

X-omics festival 2021

Save the date!

The third X-omics festival “the future of X-omics research is now!” will take place on Monday April 12th 2021. This event will take place in Nijmegen, the Netherlands or online (depending on the corona measures that apply in April 2021).

Registration for the festival is already open. In the registration you can indicate in what type of set up (in-person or online) you would like to join.

Olaf Riess, professor Medical Genetics at the University of Tübingen, Germany, will be the keynote speaker of this third edition and he will talk about “Diagnostics of Rare Diseases: Beyond the exome”

Have a look at our festival page for more information about the event and our speaker(s).
More details about the program will follow soon.

Make sure to register yourself via the button below:

Registration X-omics festival 2021

X-omics @ online events

In October, X-omics will be present at three online conferences, HUPO2020, BioSB2020 and Metabolomics2020.

During these online conferences, X-omics will be presenting its virtual booth in the exhibit halls. Our staff is present to answer any specific questions you have via chats and to videotalk to you!

Not attending any of these events and want to check out our virtual booth? No problem, you can find it here.

On October 28th, Peter-Bram ‘t Hoen (leader of the X-omics data pillar), will present in the parallel topic session “ELIXIR-NL: FAIR resources and training”. He will talk about “Applying the FAIR Data principles to a Rare Disease registry: a case study of the VASCA registry.” Go check out this presentation at 10:15 AM CET.

Also, make sure to check out the poster sessions, a lot of excellent work done by other consortium members will be shown here.

Consortium members Karlien Coene and Purva Kulkarni will be present to show their latest work during the poster sessions:

• 175, “Identification of novel diagnostic biomarkers for classical homocystinuria through untargeted metabolomics/next generation metabolic screening” by Karlien Coene, Radboudumc.
• 228, “Towards precision diagnostics: Untargeted metabolomics for the diagnosis of inborn errors of metabolism in individual patients” by Purva Kulkarni, Radboudumc.

We hope to see you online during these conferences!

Evidence for 28 genetic disorders discovered by combining healthcare and research data

A  collaboration between X-omics partner Radboudumc, GeneDx and the Wellcome Sanger Institute has discovered 28 genes that can be linked to developmental disorders.

Exome-sequence datasets from the three different institutes were combined into a cohort of 31,058 patients in order to have more statistical power. It became the largest statistical study of these mutations to date.

The approach and results of this work have been published in the scientific journal Nature. See the link below for the full article.

X-omics consortium member Christian Gilissen jointly supervised this great work and several other consortium members were involved.

View article

Summary X-omics festival 2020

On September 28th, X-omics organized the second edition of the X-omics festival “the future of X-omics research is now!”.

The event contained a keynote lecture about the 100,000 Genomes Project, lectures from young investigators, lectures with reference to several application areas and technology pitches.

The second X-omics festival was a success and we thank all the speakers, the sponsors and the participants.

An overview of the highlights, key take home messages, presentations and a link to the festival recordings has been compiled and can be found at our festival page.

We hope to see you again during future X-omics events.

Recap festival 2020

NWO logoThis research was (partially) funded by NWO, project 184.034.019